|The RNF168 n/a (Catalog #MBS6002112) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RNF168, CT (RNF168, E3 ubiquitin-protein ligase RNF168, RING finger protein 168) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s RNF168 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500. Researchers should empirically determine the suitability of the RNF168 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
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The complex repair response elicited by DNA double-strand breaks (DSBs) includes recruitment of several DNA repair proteins and ubiquitination of H2A-type histones (see MIM 142720). RNF168 is an E3 ubiquitin ligase critical for DSB repair (Stewart et al., 2009 [PubMed 19203578]).
Immunogen: RNF168 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467-496 amino acids from the C-terminal region of human RNF168. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing RNF168 are readily searchable from our website. Different antibodies against the same target such as RNF168 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.