anti-RPS6KA2 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-RPS6KA2 antibody; RPS6KA2; RIBOSOMAL S6 KINASE 2;
The RPS6KA2 rps6ka2 (Catalog #MBS502164) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Ribosomal S6 Kinase 2 reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Ribosomal S6 kinase 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Quality Control: Western Blots performed on each lot.
WB: 1:1000. Researchers should empirically determine the suitability of the RPS6KA2 rps6ka2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The RPS6KA2 rps6ka2 product has the following accession number(s) (GI #6755374) (NCBI Accession #NP_035429.1) (Uniprot Accession #Q9WUT3). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-Ribosomal S6 Kinase 2 with the following immunoassay(s):
Testing Data
Affinity purified rabbit polyclonal antibody.
Antigen: Peptide corresponding to amino acid residues from the C-terminal region of rat ribosomal S6 kinase 2, conjugated to keyhole limpet hemocyanin (KLH).
Immunogen Information: Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH
Immunogen Species: Mouse. Reactivity Assumed Based on 100% Sequence Homology: Bovine, canine, chicken, mouse and rat
Species Reactivity Note: The antibody has been demonstrated to work in human tissue. It is anticipated that the antibody will work in bovine, canine, chicken, mouse and rat tissues based on the fact that these species have 100% homology with the amino acid sequence used as antigen.
Biological Significance: The p90 ribosomal S6 kinases (RSK)1-4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits (Hanauer and Young, 2002). Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling (Sheffler et al., 2006). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing RPS6KA2 are readily searchable from our website. Different antibodies against the same target such as RPS6KA2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Embryonic Tissue, Other, Ovary, Pancreas tissues are correlated with this protein.