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anti-RTN4 antibody product blog

Posted on 2016-09-07 22:37:41 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; anti-RTN4 antibody; RTN4;
The RTN4 rtn4 (Catalog #MBS126439) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RTN4 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s RTN4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:100. Researchers should empirically determine the suitability of the RTN4 rtn4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The RTN4 rtn4 product has the following accession number(s) (GI #17369290) (NCBI Accession #Q9NQC3.2) (Uniprot Accession #Q9NQC3). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the RTN4 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts of various cell lines, using RTN4 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.)
Western Blot (WB) RTN4.

This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

Species: Human
Immunogen: Recombinant Protein. Immunogen: Fusion protein of human RTN4
Calculated Molecular Weight: 130kDa. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing RTN4 are readily searchable from our website. Different antibodies against the same target such as RTN4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Atherosclerosis, Carcinoma, Cardiovascular Diseases, Disease Models, Animal, Heart Diseases, Hypertension, Liver Diseases, Movement Disorders, Nervous System Diseases, Schizophrenia are some of the diseases may be linked to RTN4 Polyclonal Antibody. Blood, Brain, Embryonic Tissue, Eye, Heart, Kidney, Liver, Muscle, Nerve, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene.
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