Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Polyclonal Antibody Blog  rightarrow anti-RXRA antibody  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Blogs moreseparator
separator
 • anti-TUBB antibody blog
 • anti-ATIC antibody blog
 • anti-ACTN2 antibody blog
 • anti-F8 antibody blog
 • anti-C11orf30 antibody blog
 • anti-4E-BP1 antibody blog
 • anti-ARL8A antibody blog
 • anti-BAMBI antibody blog
 • anti-DDX3X antibody blog
 • anti-ERK1 antibody blog
 • anti-TAAR5 antibody blog
 • anti-CDKN1A antibody blog
 • anti-IFNL4 antibody blog
 • anti-KLF4 antibody blog
 • anti-CSRP2 antibody blog
 • anti-Ubiquitin Conjugating Enzyme E2L3 antibody blog
 • anti-NOX1 antibody blog
 • anti-MCAM antibody blog
 • anti-ELMOD2 antibody blog
 • anti-DSC1 antibody blog
separator
Blog Categories separator
separator
 • Assay Kit Blogs
 • Biochemical Blogs
 • cDNA Clone Blogs
 • Monoclonal Antibody Blogs
 • Polyclonal Antibody Blogs
 • Rec/Purified Protein Blogs
 • Popular Product Blogs
separator
Our Best Sellers moreseparator
separator
 • Androgen Receptor (AR) Antibody
 • Mucin 5 Subtype AC (MUC5AC) ELISA Kit
 • Cardiac Myosin-Light Chains 1 (CMIC-1) ELISA Kit
 • BTLA cDNA Clone
 • 1-aminocyclopropane-1-carbo xylate synthase-like protein 1 (A... ELISA Kit
 • Actin-related protein 2-3 complex subunit 3 (ARPC3) Recombinant Protein
 • olfactomedin 2 (OLFM2) ELISA Kit
 • Complement C3 Antibody
 • TK1 Recombinant Protein
 • ADAM metallopeptidase with thrombospondin type 1 motif, 3 (A... ELISA Kit
 • beta-Thromboglobulin (beta-TG) ELISA Kit
 • odontogenic, ameloblast asssociated (ODAM) ELISA Kit
 • albumin ELISA Kit
 • IRF9 Antibody
 downarrow more ...
separator

anti-RXRA antibody product blog

separator
Posted on 2015-09-01 23:06:23 by mybiosource_staff
Share it on ...     
separator
separator
Tags: Antibody; Polyclonal Antibody; RXRA; anti-RXRA antibody;
separator
The RXRA rxra (Catalog #MBS129323) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RXRA Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s RXRA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).
WB: 1:200 - 1:2000
IHC: 1:100 - 1:200
IF: 1:50 - 1:100. Researchers should empirically determine the suitability of the RXRA rxra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The RXRA rxra product has the following accession number(s) (GI #133701) (NCBI Accession #P19793.1) (Uniprot Accession #P19793). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the RXRA Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts of MCF-7 cells, using RXRA antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.)
Western Blot (WB) RXRA.

Retinoid X receptor alpha (RXRA). Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5\'-AGGTCA-3\' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. RXRA serves as a common heterodimeric partner for a number of nuclear receptors. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5\'-AGGTCA-3\' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. The RXRA/PPARA heterodimer is required for PPARA transcriptional activity on fatty acid oxidation genes such as ACOX1 and the P450 system genes. This antibody is a rabbit polyclonal antibody raised against the 350 AA of human RXRA C-terminal. RXRA is highly expressed in liver, also expressed in lung, kidney and heart. It specifically recognizes the 51kd human RXRA protein.

Species: Human
Immunogen: Recombinant Protein. Immunogen: Recombinant protein of human RXRA
Calculated Molecular Weight: 51kDa. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing RXRA are readily searchable from our website. Different antibodies against the same target such as RXRA may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions