|The SARS, Spike Protein n/a (Catalog #MBS629627) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s SARS, Spike Protein can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA).
Suitable for use in ELISA.
Dilution: ELISA: Detects 10ng of free peptide at 1ug/ml.
Optimal dilution determined by the researcher. Researchers should empirically determine the suitability of the SARS, Spike Protein n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SARS, Spike Protein n/a product has the following accession number(s) (GI #89514837) (NCBI Accession #ABD75332.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
A novel coronavirus has recently been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome) (1-2). Coronaviruses are a major cause of upper respiratory diseases in humans (3). The genomes of these viruses are positive-stranded RNA approximately 27-31kb in length. SARS infection can be mediated by the binding of the viral spike protein, a glycosylated 139kD protein and the major surface antigen of the virus, to the angiotensin-converting enzyme 2 (ACE2) on target cells. This binding can be blocked by a soluble form of ACE2 (4).
Immunogen: Synthetic peptide corresponding to amino acids 426-441 of the SARS Spike glycoprotein (Genbank accession no. P59594). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SARS, Spike Protein are readily searchable from our website. Different antibodies against the same target such as SARS, Spike Protein may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.