|The Scytovirin svn (Catalog #MBS7005164) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Scytovirin Antibody; HRP conjugated reacts with Scytonema varium and may cross-react with other species as described in the data sheet. MyBioSource\'s Scytovirin can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the Scytovirin svn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Scytovirin svn product has the following accession number(s) (GI #209573788) (NCBI Accession #P86041.1) (Uniprot Accession #P86041). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Has strong anti-HIV activity against T-tropic strains of HIV-1 and weaker activity against M-tropic strains of HIV-1. Inhibits HIV-1 fusion and infection of CD4 LTR beta-gal cells in vitro. Inhibits fusion of HIV infected CEM-SS cells with uninfected CEM-SS cells, and fusion of HIV-1 Env expressing HL2/3 cells with CD4 LTR beta-gal cells. Binds to HIV gp120, HIV gp160 and to a lesser extent HIV gp41. Binding to HIV gp120 is glycosylation dependent. Binds with high specificity to the tetrasaccharide Man-alpha-1,2-Man-alpha-1,6-Man-alpha-1,6-Man and also binds the higher-order oligosaccharides oligomannose 8 and oligomannose 9. Does not bind to monosaccharides, complex or hybrid N-linked oligosaccharides or chitin.
Immunogen: Recombinant Scytonema varium Scytovirin protein. Conjugation: HRP
Storage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Scytovirin are readily searchable from our website. Different antibodies against the same target such as Scytovirin may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.