|The SDHAF1 sdhaf1 (Catalog #MBS627158) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Succinate Dehydrogenase Complex Assembly Factor 1, SDHAF1 reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Succinate Dehydrogenase Complex Assembly Factor 1, SDHAF1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in ELISA and Western Blot.
Dilution: Peptide ELISA Titer: 1:16,000
Western Blot: 0.3-1ug/ml detects ~19kD band observed in Human Brain (Cerebellum) lysates (calculated MW of 12.8kD according to NP_001036096.1). Researchers should empirically determine the suitability of the SDHAF1 sdhaf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SDHAF1 sdhaf1 product has the following accession number(s) (GI #111038124) (NCBI Accession #NP_001036096.1) (Uniprot Accession #A6NFY7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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The succinate dehydrogenase (SDH) complex (or complex II) of the mitochondrial respiratory chain is composed of 4 individual subunits. The protein encoded by this gene resides in the mitochondria, and is essential for SDH assembly, but does not physically associate with the complex in vivo. Mutations in this gene are associated with SDH-defective infantile leukoencephalopathy (mitochondrial complex II deficiency).
Immunogen: Synthetic peptide corresponding to C-HDSTGAPETRPDGR, from the C-Terminus of human SDHAF1 (NP_001036096.1). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SDHAF1 are readily searchable from our website. Different antibodies against the same target such as SDHAF1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Brain, Kidney, Muscle tissues are correlated with this protein. SDHAF1 also interacts with the following gene(s): ROMO1, SDHA. Mitochondrial Complex II Deficiency are some of the diseases may be linked to Succinate Dehydrogenase Complex Assembly Factor 1, SDHAF1.