anti-SEPT4 antibody product blog
Tags: Antibody; Polyclonal Antibody; ARTS; SEPT4; anti-SEPT4 antibody;
The SEPT4 sept4 (Catalog #MBS150658) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ARTS Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ARTS can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).ARTS antibody can be used for detection of ARTS by Western blot at 2 mug/mL. A band at 32 kDa can be detected. Antibody can also be used for immunohistochemistry starting at 2 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the SEPT4 sept4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SEPT4 sept4 product has the following accession number(s) (GI #12024871) (NCBI Accession #AAG45673) (Uniprot Accession #O43236). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ARTS Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of ARTS expression in human lung (lane 1), spleen (lane 2), and kidney (lane 3) tissue lysates with ARTS antibody at 2 μg /ml.)
Immunohistochemistry (IHC) (Immunohistochemistry of ARTS in human lung tissue with ARTS antibody at 2 μg/mL.)
Immunofluorescence (IF) (Immunofluorescence of ARTS in Human Lung cells with ARTS antibody at 20 μg/mL.)
ARTS Antibody: Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents, such as TNF-α and Fas ligand.
Conjugate: Unconjugated
Immunogen: ARTS antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human ARTS.
Buffer: ARTS Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SEPT4 are readily searchable from our website. Different antibodies against the same target such as SEPT4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.