anti-SERPINC1 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-SERPINC1 antibody; SERPINC1; Antithrombin III;
The SERPINC1 serpinc1 (Catalog #MBS176991) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Antithrombin III antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Antithrombin III can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the SERPINC1 serpinc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The SERPINC1 serpinc1 product has the following accession number(s) (GI #113936) (NCBI Accession #P01008.1) (Uniprot Accession #P01008). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-Antithrombin III antibody with the following immunoassay(s):
Western Blot (WB) (Anti-Antithrombin III antibody, MBS176991, Western blotting
Lane 1: Rat Testis Tissue Lysate
Lane 2: SMMC Cell Lysate
Lane 3: JURKAT Cell Lysate
Lane 4: RAJI Cell Lysate )
Description: Rabbit IgG polyclonal antibody for Antithrombin-III(SERPINC1) detection. Tested with WB in Human, Mouse, Rat.
Background: Serpin peptidase inhibitor, clade C(antithrombin), member 1, also known as Antithrombin III(AT3) is the most important inhibitor of thrombin OMBIN III and other coagulation proteinases. This gene is mapped to 1q25.1. The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Antithrombin III (93-107aa TFYQHLADSKNDNDN), different from the related mouse and rat sequences by one amino acid. Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SERPINC1 are readily searchable from our website. Different antibodies against the same target such as SERPINC1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.