|The SH3PXD2A sh3pxd2a (Catalog #MBS9202152) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SH3PXD2A Antibody (N-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. MyBioSource\'s SH3PXD2A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).
WB~~1:1000. Researchers should empirically determine the suitability of the SH3PXD2A sh3pxd2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SH3PXD2A sh3pxd2a product has the following accession number(s) (GI #55749544) (NCBI Accession #NP_055446.2) (Uniprot Accession #Q5TCZ1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the SH3PXD2A Antibody (N-term) with the following immunoassay(s):
Western Blot (WB) (SH3PXD2A Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SH3PXD2A antibody detected the SH3PXD2A protein (arrow).)
SH3PXD2A is required for podosome formation, degradation of the extracellular matrix, and for the invasiveness of some cancer cells. Binds phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 3,4-biphosphate (PtdIns(3,4)P2). In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide.
Antigen Type: Synthetic Peptide. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SH3PXD2A are readily searchable from our website. Different antibodies against the same target such as SH3PXD2A may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. SH3PXD2A also interacts with the following gene(s): CDC42, CTTN, RAC1, SRC, SVIL. Breast Neoplasms, Congenital Abnormalities, Neoplasm Metastasis, Nervous System Diseases, Prostatic Neoplasms are some of the diseases may be linked to SH3PXD2A Antibody (N-term). Blood, Bone, Brain, Embryonic Tissue, Heart, Lung, Muscle, Placenta, Prostate, Vascular tissues are correlated with this protein.