anti-SIN3B antibody product blog
Tags: Antibody; Polyclonal Antibody; SIN3B; anti-SIN3B antibody;
The SIN3B sin3b (Catalog #MBS9412738) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SIN3B Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s SIN3B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF).Western blotting: 1:500~1:3000
Immunofluorescence: 1:100~1:500. Researchers should empirically determine the suitability of the SIN3B sin3b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SIN3B sin3b product has the following accession number(s) (GI #662236753) (NCBI Accession #NP_001284524.1) (Uniprot Accession #O75182). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the SIN3B Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts from A549 cells, using SIN3B antibody.)
Immunofluorescence (IF) (Immunofluorescence analysis of HeLa cells, using SIN3B antibody.)
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription By similarity.Ishikawa K., DNA Res. 5:169-176(1998).The MGC Project Team, Genome Res. 14:2121-2127(2004).Wysocka J., Genes Dev. 17:896-911(2003).
Immunogen Type: Peptide
Immunogen Description: Synthesized peptide derived from internal of human SIN3B. Target Name: SIN3B. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SIN3B are readily searchable from our website. Different antibodies against the same target such as SIN3B may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Atherosclerosis, Atrophy, Breast Neoplasms, Embryo Loss, Inflammation, Liver Diseases, Mammary Neoplasms, Animal, Mammary Neoplasms, Experimental, Neoplasm Metastasis, Skin Diseases are some of the diseases may be linked to SIN3B Antibody. SIN3B also interacts with the following gene(s): HDAC1, HDAC2, NCOR1, RBBP4. The following patways have been known to be associated with this gene. Brain, Embryonic Tissue, Epididymis, Eye, Heart, Kidney, Liver, Muscle, Nerve, Ovary tissues are correlated with this protein.