anti-SIRT4 antibody product blog
Tags: Antibody; Polyclonal Antibody; SIRT4; anti-SIRT4 antibody;
The SIRT4 sirt4 (Catalog #MBS9405195) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SIRT4 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s SIRT4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the SIRT4 sirt4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The SIRT4 sirt4 product has the following accession number(s) (GI #119618588) (NCBI Accession #EAW98182). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the SIRT4 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of SIRT4 in human liver tissue lysate with SIRT4 antibody at 1 ug/mL.)
The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT4 localizes to mitochondria, inhibits glutamate dehydrogenase, and is thought to be involved in the regulation of insulin secretion.
Immunogen Type: Peptide
Immunogen Description: Raised against a 17 amino acid peptide near the amino terminus of human SIRT4. Target Name: SIRT4. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SIRT4 are readily searchable from our website. Different antibodies against the same target such as SIRT4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Abnormalities, Drug-Induced, Cardiovascular Diseases, Fatty Liver, Fibrosis, Heart Diseases, Hypertrophy, Inflammation, Lung Diseases, Necrosis, Proteinuria are some of the diseases may be linked to SIRT4 Antibody. SIRT4 also interacts with the following gene(s): HDAC10, HDAC11, HDAC6, HDAC9, MTOR, SIRT3. The following patways have been known to be associated with this gene. Brain, Heart, Kidney, Liver, Lung, Muscle tissues are correlated with this protein.