anti-slc10A2 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-SLC10A2 antibody; SLC10A2; Solute Carrier Family 10;
The slc10A2 n/a (Catalog #MBS622028) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Solute Carrier Family 10 (SLC10A2, sodium/bile acid cotransporter family), member 2; ASBT; ISBT; ileal apical sodium-dependent bile acid transporter; ileal sodium-dependent bile acid transporter; solute carrier family 10, member 2) reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Solute Carrier Family 10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:32,000. Researchers should empirically determine the suitability of the slc10A2 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The slc10A2 n/a product has the following accession number(s) (GI #291615801) (NCBI Accession #YP_003518543.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Solute Carrier Family 10 (SLC10A2, sodium/bile acid cotransporter family), member 2; ASBT; ISBT; ileal apical sodium-dependent bile acid transporter; ileal sodium-dependent bile acid transporter; solute carrier family 10, member 2) with the following immunoassay(s):
Chemiluminescence (EB08819 (0.5µg/ml) staining of Mouse Small Intestine lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
SLC10A2 plays a critical role in reabsorption of bile acids from the the small intestine lumen. Passive flow of sodium ions down their concentration gradient is coupled to bile acid movement, resulting in an increase in the concentration of bile acids in the interior of the cell. This action conserves the body\'s pool of re-circulating bile acid. SLC10A2 also plays a key role in cholesterol metabolism as cholesterol is the precursor molecule in bile acid synthesis mediated by CYP7A and FXR.
Immunogen: Synthetic peptide corresponding to C-DETNKGFQPDEK, from the C Terminus of mouse SLC10A2 (NP_035518.1). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing slc10A2 are readily searchable from our website. Different antibodies against the same target such as slc10A2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.