anti-SLC2A4 antibody product blog
Tags: Antibody; Polyclonal Antibody; SLC2A4; anti-SLC2A4 antibody;
The SLC2A4 slc2a4 (Catalog #MBS9128287) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC2A4 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s SLC2A4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).WB 1:500 - 1:2000
IHC 1:50 - 1:200. Researchers should empirically determine the suitability of the SLC2A4 slc2a4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SLC2A4 slc2a4 product has the following accession number(s) (GI #4507011) (NCBI Accession #NP_001033.1) (Uniprot Accession #P14672). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the SLC2A4 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts of various cell lines, using SLC2A4 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded mouse heart using SLC2A4 antibody at dilution of 1:100 (40x lens).)
Background/Introduction: This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).
In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SLC2A4 are readily searchable from our website. Different antibodies against the same target such as SLC2A4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Cardiovascular Diseases, Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 2, Disease Models, Animal, Glucose Intolerance, Heart Diseases, Hyperglycemia, Hyperinsulinism, Insulin Resistance, Necrosis are some of the diseases may be linked to SLC2A4 Polyclonal Antibody.