|The SLC46A1 slc46a1 (Catalog #MBS646076) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The SLC46A1 (Proton-coupled Folate Transporter, G21, Heme Carrier Protein 1, PCFT/HCP1, Solute Carrier Family 46 Member 1, HCP1, PCFT) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s SLC46A1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC).
Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 3.75ug/ml. Researchers should empirically determine the suitability of the SLC46A1 slc46a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SLC46A1 slc46a1 product has the following accession number(s) (GI #14715055) (NCBI Accession #AAH10691.1) (Uniprot Accession #Q96NT5). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Has been shown to act both as an intestinal proton-coupled high-affinity folate transporter and as an intestinal heme transporter which mediates heme uptake from the gut lumen into duodenal epithelial cells. The iron is then released from heme and may be transported into the bloodstream. Dietary heme iron is an important nutritional source of iron. Shows a higher affinity for folate than heme.
Immunogen: Synthetic peptide corresponding to human SLC46A1. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SLC46A1 are readily searchable from our website. Different antibodies against the same target such as SLC46A1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Embryonic Tissue, Eye, Heart, Intestine, Kidney, Liver, Lung, Pancreas, Placenta tissues are correlated with this protein. SLC46A1 also interacts with the following gene(s): FOLR1, FPGS, GGH, HMOX1, SLC11A2, SLC19A1, SLC19A3. Anemia, Brain Diseases, Cardiovascular Diseases, Hyperhomocysteinemia, Inflammation, Kidney Diseases, Malabsorption Syndromes, Nervous System Diseases, Neural Tube Defects, Seizures are some of the diseases may be linked to SLC46A1 (Proton-coupled Folate Transporter, G21, Heme Carrier Protein 1, PCFT/HCP1, Solute Carrier Family 46 Member 1, HCP1, PCFT). The following patways have been known to be associated with this gene.