anti-SLITRK6 antibody product blog
Tags: Antibody; Polyclonal Antibody; SLITRK6; anti-SLITRK6 antibody;
The SLITRK6 slitrk6 (Catalog #MBS620322) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Slitrk6, CT (SLIT and NTRK-like family 6, FLJ22774, FLJ22774, MGC119595, MGC119596, MGC119597, SLIT and NTRK-like protein 6 precursor) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Slitrk6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Dilution: Western Blot: 0.5-1ug/ml. Researchers should empirically determine the suitability of the SLITRK6 slitrk6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SLITRK6 slitrk6 product has the following accession number(s) (GI #40217825) (NCBI Accession #NP_115605.2) (Uniprot Accession #Q9H5Y7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Slitrk6, CT (SLIT and NTRK-like family 6, FLJ22774, FLJ22774, MGC119595, MGC119596, MGC119597, SLIT and NTRK-like protein 6 precursor) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of Slitrk6 in SK-N-SH cell lysate with Slitrk6 antibody at (A) 0.5 and (B) 1 ug/ml.)
SLIT and NTRK-like family 6 (Slitrk6) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains (1). Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family (1,2). Slitrk6 expression has been observed in tissues such as tongue, lung, gastrointestinal tract, and pancreas (3). Like every other Slitrk protein except Slitrk1, overexpression of Slitrk6 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.
Immunogen: Synthetic peptide corresponding to 16aa from near the carboxy terminus of human Slitrk6 (GenBank accession no. Q9H5Y7). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SLITRK6 are readily searchable from our website. Different antibodies against the same target such as SLITRK6 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.