anti-SMARCD1 antibody product blog
Tags: Antibody; Polyclonal Antibody; SMARCD1; anti-SMARCD1 antibody;
The SMARCD1 smarcd1 (Catalog #MBS642826) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Smarcd1, ID (Smarcd1, Baf60a, D15Kz1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1, 60kD BRG-1/Brm-associated factor subunit A, BRG1-associated factor 60A, Protein D15KZ1, SWI/SNF complex 60kD subunit) reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Smarcd1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500. Researchers should empirically determine the suitability of the SMARCD1 smarcd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SMARCD1 smarcd1 product has the following accession number(s) (GI #133908631) (NCBI Accession #NP_620710.2) (Uniprot Accession #Q96GM5). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Smarcd1, ID (Smarcd1, Baf60a, D15Kz1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1, 60kD BRG-1/Brm-associated factor subunit A, BRG1-associated factor 60A, Protein D15KZ1, SWI/SNF complex 60kD subunit) with the following immunoassay(s):
Western Blot (WB) (Mouse Smarcd1 Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Mouse Smarcd1 antibody detected the Mouse Smarcd1 protein (arrow).)
Smarcd1 is involved in chromatin remodeling. Has a strong influence on the Vitamin D-mediated transcriptional activity from an enhancer Vitamin D receptor element (VDRE). May be a link between mammalian SWI-SNF-like chromatin remodeling complexes and the vitamin D receptor (VDR) heterodimer. Mediates critical interactions between nuclear receptors and the BRG1/SMARCA4 chromatin-remodeling complex for transactivation. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene (By similarity). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.