anti-SNCA antibody product blog
Tags: Antibody; SNCA; Polyclonal Antibody; anti-SNCA antibody;
The SNCA snca (Catalog #MBS153543) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SNCA Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s SNCA can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).SNCA antibody can be used for detection of SNCA by Western blot at 1 - 2 ug/ml. Antibody can also be used for Immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
Optimal dilutions for each application to be determined by the researcher.
Positive control: 1) Mouse Cerebellum Tissue Lysate. Researchers should empirically determine the suitability of the SNCA snca for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SNCA snca product has the following accession number(s) (GI #6806898) (NCBI Accession #NP_000336) (Uniprot Accession #P37840). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the SNCA Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of SNCA in mouse cerebellum tissue lysate with SNCA antibody at 1 μg/ml.)
Immunohistochemistry (IHC) (Immunohistochemistry of SNCA in rat brain tissue with SNCA antibody at 5 μg/ml.)
Immunofluorescence (IF) (Immunofluorescence of SNCA in rat brain tissue with SNCA antibody at 20 μg/ml.)
Western Blot (WB) (Western blot analysis of 1 ng of recombinant human SNCA with SNCA antibody at 1 μg/ml.)
Alpha-Synuclein (SNCA) is a hallmark of Alzheimer\'s disease (1,2). It is a cytoplasmic protein that is predominantly expressed in the central nervous system (2). SNCA reduces neuronal responsiveness to various apoptotic stimuli, leading to the decreased caspase-3 activation. SNCA may be involved in the regulation of dopamine release and transport and induces fibrillization of microtubule-associated protein tau (3). Defects in SNCA are associated with familial Parkinson\'s disease (4,5).
Conjugate: Unconjugated
Immunogen: SNCA antibody was raised against a 19 amino acid peptide near the carboxy terminus of human SNCA.
The immunogen is located within the last 50 amino acids of SNCA.
Buffer: SNCA antibody is supplied in PBS containing 0.02% sodium azide. Homoglogy: Predicted species reactivity based on immunogen sequence: Pig: (100%), Bovine: (100%). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SNCA are readily searchable from our website. Different antibodies against the same target such as SNCA may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.