anti-STAT2 antibody product blog
Tags: Antibody; STAT2; Polyclonal Antibody; anti-STAT2 antibody; STAT 2;
The STAT2 stat2 (Catalog #MBS624061) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Stat 2, CT (Signal Transducer And Activator Of Transcription 2, p113) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Stat 2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC).Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100. Researchers should empirically determine the suitability of the STAT2 stat2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The STAT2 stat2 product has the following accession number(s) (GI #1293920) (Uniprot Accession #P52630). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Stat 2, CT (Signal Transducer And Activator Of Transcription 2, p113) with the following immunoassay(s):
Immunohistochemistry (IHC) (STAT2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the STAT2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Western Blot (WB) (Western blot analysis of STAT2 Antibody (C-term) in K562 cell line lysates (35ug/lane). STAT2(arrow) was detected using the purified Pab.)
STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.
Immunogen: Synthetic peptide selected from the C-terminal region of human STAT2 (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing STAT2 are readily searchable from our website. Different antibodies against the same target such as STAT2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.