anti-SUV420H1 antibody product blog
Tags: Antibody; Polyclonal Antibody; Suv420h1; HEY 2; anti-SUV420H1 antibody;
The SUV420H1 suv420h1 (Catalog #MBS618756) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HEY 2 (Helix-loop-helix Transcription Factor, Hairy/enhancer-of-split related with YRPW motif 2, bHLHb32, BHLHB32, Cardiovascular helix-loop-helix factor 1, CHF1, Class B basic helix-loop-helix protein 32, GRIDLOCK, GRL, Hairy and enhancer of split-relate reacts with Human, Rodent and may cross-react with other species as described in the data sheet. MyBioSource\'s HEY 2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC).Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry: 1:200-1:1000. Researchers should empirically determine the suitability of the SUV420H1 suv420h1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SUV420H1 suv420h1 product has the following accession number(s) (GI #50659084) (NCBI Accession #NP_057112.3) (Uniprot Accession #Q4FZB7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
The Hey family of bHLH transcription factors are direct targets of Notch signaling. HEY2 (gridlock) is an important determinant of mammalian heart development, loss of which in mouse leads to cardiac defects with high postnatal lethality. Mouse Hey1 knockouts have no apparent phenotypic defect but the combined loss of Hey1 and Hey2 results in embryonic death after embryonic day 9.5 (E9.5) with a global lack of vascular remodeling and massive hemorrhage. Similar defects are observed in Jagged1 and Notch1 knockout mice.
Immunogen: Synthetic peptide corresponding to aa314-330 of human Hey 2/HRT2. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SUV420H1 are readily searchable from our website. Different antibodies against the same target such as SUV420H1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Neoplasms are some of the diseases may be linked to HEY 2 (Helix-loop-helix Transcription Factor, Hairy/enhancer-of-split related with YRPW motif 2, bHLHb32, BHLHB32, Cardiovascular helix-loop-helix factor 1, CHF1, Class B basic helix-loop-helix protein 32, GRIDLOCK, GRL, Hairy and enhancer of split-relate. The following patways have been known to be associated with this gene. Blood, Brain, Muscle tissues are correlated with this protein.