|The SYCP3 sycp3 (Catalog #MBS9408298) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SYCP3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s SYCP3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the SYCP3 sycp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SYCP3 sycp3 product has the following accession number(s) (GI #295789050) (NCBI Accession #NP_001171419.1) (Uniprot Accession #Q8IZU3). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the SYCP3 Antibody with the following immunoassay(s):
Testing Data (Gel: 12%SDS-PAGE Lysates (from left to right): Human testis and seminoma tissue, Jurkat cell and human liver cancer tissue Amount of lysate: 40ug per lane Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 40 seconds)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/20.)
This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein.
Immunogen Type: Peptide
Immunogen Description: Synthetic peptide corresponding to residues near the C terminal of human synaptonemal complex protein 3. Target Name: SYCP3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SYCP3 are readily searchable from our website. Different antibodies against the same target such as SYCP3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Connective Tissue, Embryonic Tissue, Kidney, Lung, Placenta, Prostate, Testis tissues are correlated with this protein. SYCP3 also interacts with the following gene(s): H2AFX, HSPA2, REC8, SMC3, STAG3, SYCE1, SYCE2, SYCP1, SYCP2. Abortion, Habitual, Atrophy, Azoospermia, Breast Neoplasms, Carcinoma, Disease Models, Animal, Embryo Loss, Neoplasm Metastasis, Oligospermia, SPERMATOGENIC FAILURE 4 are some of the diseases may be linked to SYCP3 Antibody. The following patways have been known to be associated with this gene.