|The TGFBR3 tgfbr3 (Catalog #MBS615346) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Transforming Growth Factor beta Receptor III (TGF beta Receptor III, TGF beta RIII, TGFR-3, Betaglycan) (Carboxyfluorescein) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Transforming Growth Factor beta Receptor III can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS).
Suitable for use in Flow Cytometry.
Dilution: Flow Cytometry: Neat. Use 10ul to label 10e6 cells. Researchers should empirically determine the suitability of the TGFBR3 tgfbr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TGFBR3 tgfbr3 product has the following accession number(s) (GI #119593519) (Uniprot Accession #Q03167). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Most cell types express three different sizes of TGF-Beta receptors. These are designated Type I (53kD), Type II (70-85kD), and Type III (250-350kD). The Type I receptor is a membrane-bound serine/threonine kinase that apparently requires the presence of the Type II receptor to bind TGF-Beta. The Type II receptor is also a membrane-bound serine/ threonine kinase that binds TGF-Beta1 and TGF-Beta3 with high affinity and TGF-Beta2 with a much lower affinity. The Type I and Type II receptors together form a heterodimeric signaling complex that is essential for the transduction of the anti-proliferative signals of TGF-Beta.
Immunogen: NS0-derived recombinant human TGF-beta sRIII extracellular domain. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TGFBR3 are readily searchable from our website. Different antibodies against the same target such as TGFBR3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Adenocarcinoma, Breast Neoplasms, Carcinoma, Fibrosis, Gonadal Disorders, Inflammation, Lung Neoplasms, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms are some of the diseases may be linked to Transforming Growth Factor beta Receptor III (TGF beta Receptor III, TGF beta RIII, TGFR-3, Betaglycan) (Carboxyfluorescein). Blood, Bone, Brain, Connective Tissue, Kidney, Lung, Muscle, Ovary, Pituitary Gland, Vascular tissues are correlated with this protein.