|The THPO thpo (Catalog #MBS126998) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The THPO Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s THPO can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200. Researchers should empirically determine the suitability of the THPO thpo for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The THPO thpo product has the following accession number(s) (GI #730982) (NCBI Accession #P40225.1) (Uniprot Accession #P40225). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the THPO Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts of various cell lines, using THPO antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.)
Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternate splicing results in multiple transcript variants of this gene.[provided by RefSeq, Jun 2012].
Immunogen: Recombinant Protein. Immunogen: Recombinant protein of human THPO
Calculated Molecular Weight: 38kDa. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing THPO are readily searchable from our website. Different antibodies against the same target such as THPO may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. THPO also interacts with the following gene(s): KITLG, MPL, SELP. Connective Tissue, Liver tissues are correlated with this protein. The following patways have been known to be associated with this gene. Anemia, Carcinoma, Squamous Cell, Cardiovascular Diseases, Congenital Abnormalities, Hypertension, Lung Neoplasms, Pain, Precancerous Conditions, Thrombocythemia, Essential, Thrombocytosis are some of the diseases may be linked to THPO Polyclonal Antibody.