anti-TIE1 antibody product blog
Tags: Antibody; Polyclonal Antibody; TIE1; anti-TIE1 antibody; Tyrosine-protein kinase receptor TIE1;
The TIE1 tie1 (Catalog #MBS355080) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Tyrosine-protein kinase receptor TIE1 antibody reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Tyrosine-protein kinase receptor TIE1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC).WB (1:5000); ICC (1:100-500); Flow Cytometryt (1:10-100). Researchers should empirically determine the suitability of the TIE1 tie1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TIE1 tie1 product has the following accession number(s) (GI #4885631) (NCBI Accession #NP_005415.1) (Uniprot Accession #P35590). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-Tyrosine-protein kinase receptor TIE1 antibody with the following immunoassay(s):
Western Blot (WB)
Tyrosine kinase with immunoglobulin-like and EGF-like domains 1, TIE1 is an angiopoietin receptor which in humans is encoded by the TIE1 gene.1 The receptor tyrosine kinase Tie1 is expressed in both vascular endothelial cells and immature hematopoietic cells.2 TIE1 upregulates the cell adhesion molecules (CAMs) VCAM-1, E-selectin, and ICAM-1 through a p38-dependent mechanism. Attachment of monocyte derived immune cells to endothelial cells is also enhanced by TIE1 expression. TIE1 has a proinflammatory effect and may play a role in the endothelial inflammatory diseases such as atherosclerosis.3.
Immunogen: A synthetic peptide (conjugated with KLH) corresponding to near N-terminal of human TIE-1. Storage Buffer: In TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Buffer: In TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TIE1 are readily searchable from our website. Different antibodies against the same target such as TIE1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Brain, Embryonic Tissue, Heart, Kidney, Liver, Lung, Umbilical Cord, Vascular tissues are correlated with this protein. TIE1 also interacts with the following gene(s): ANGPT1, ANGPT2, ANGPT4, ANGPTL1, ANGPTL2, ANGPTL3, ANGPTL4, TEK, VEGFA. Bone Diseases, Brain Diseases, Edema, Hemorrhage, Inflammation, Kidney Diseases, Liver Neoplasms, Necrosis, Neoplasms, Respiratory Tract Diseases are some of the diseases may be linked to Anti-Tyrosine-protein kinase receptor TIE1 antibody.