anti-TLE1 antibody product blog
Tags: Antibody; Polyclonal Antibody; TLE1; anti-TLE1 antibody;
The TLE1 tle1 (Catalog #MBS9207891) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TLE1 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s TLE1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).WB~~1:1000. Researchers should empirically determine the suitability of the TLE1 tle1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TLE1 tle1 product has the following accession number(s) (GI #733605268) (NCBI Accession #NP_001290032.1) (Uniprot Accession #Q04724). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TLE1 Antibody (N-term) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of lysates from HepG2, MCF-7 cell line and human brain tissue(from left to right), using TLE1 Antibody (N-term). MBS9207891 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
Crown Antibody: Yes. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TLE1 are readily searchable from our website. Different antibodies against the same target such as TLE1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Adenocarcinoma, Breast Neoplasms, Carcinoma, Hepatocellular, Disease Models, Animal, Inflammation, Kidney Diseases, Liver Diseases, Liver Neoplasms, Lung Diseases, Lung Neoplasms are some of the diseases may be linked to TLE1 Antibody (N-term). TLE1 also interacts with the following gene(s): CTNNB1, FOXG1, HDAC1, HES1, HES6, LEF1, NOTCH1, SIX3, TCF7L2. Blood, Bone, Brain, Embryonic Tissue, Heart, Kidney, Liver, Lung, Muscle, Pancreas tissues are correlated with this protein.