anti-TLE4 antibody product blog
Tags: Antibody; Polyclonal Antibody; TLE4; anti-TLE4 antibody;
The TLE4 tle4 (Catalog #MBS9208525) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TLE4 Antibody (N-term) reacts with Human (Predicted Reactivity: Mouse, Rat) and may cross-react with other species as described in the data sheet. MyBioSource\'s TLE4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).WB~~1:1000. Researchers should empirically determine the suitability of the TLE4 tle4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TLE4 tle4 product has the following accession number(s) (GI #34915994) (NCBI Accession #NP_008936.2) (Uniprot Accession #Q04727). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TLE4 Antibody (N-term) with the following immunoassay(s):
Western Blot (WB) (TLE4 Antibody (N-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the TLE4 antibody detected the TLE4 protein (arrow).)
TLE4 is a transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).
Antigen Type: Synthetic Peptide. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TLE4 are readily searchable from our website. Different antibodies against the same target such as TLE4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Adenocarcinoma, Adenoma, Asthma, Carcinoma, Congenital Abnormalities, Disease Models, Animal, Hypertrophy, Lung Diseases, Neoplasms, Experimental, Precancerous Conditions are some of the diseases may be linked to TLE4 Antibody (N-term). TLE4 also interacts with the following gene(s): CREBBP, CTNNB1, HES1, OTX2, PAX5. Blood, Bone, Bone Marrow, Brain, Embryonic Tissue, Eye, Kidney, Lung, Nerve, Skin tissues are correlated with this protein.