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anti-TLR1 antibody product blog

Posted on 2018-01-12 15:42:30 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; TLR1; anti-TLR1 antibody;
The TLR1 tlr1 (Catalog #MBS540395) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TLR1 Antibody reacts with Mouse, Rat
Predicted: Human and may cross-react with other species as described in the data sheet. MyBioSource\'s TLR1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB).
ELISA: 1:20,000
Immunocytochemistry: 1:100
Immunofluorescence: 1:100
Immunohistochemistry: 1:100
Immunoprecipitation: 1:200
Western Blot: 1:500. Researchers should empirically determine the suitability of the TLR1 tlr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The TLR1 tlr1 product has the following accession number(s) (GI #13507603) (NCBI Accession #NP_109607.1) (Uniprot Accession #Q9EPQ1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TLR1 Antibody with the following immunoassay(s):
Western Blot (WB)
Western Blot (WB) TLR1.

Immunohistochemistry (IHC)
Immunohistochemistry (IHC) TLR1.

Immunohistochemistry (IHC)
Immunohistochemistry (IHC) TLR1.

Affinity Purified Toll-like receptor 1 Antibody
Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.

Immunogen: Synthetic peptide taken within amino acid region 200-250 on mouse toll-like receptor 1 protein.
Immunoglobulin: IgG. Molecular Function: Receptor, Transmembrane signaling receptor activity, triacyl lipopeptide binding
Structure: Binds MYD88 (via TIR domains) (By similarity). Interacts (via extracellular domain) with TLR2. Ligand binding induces the formation of a heterodimer with TLR2 (By similarity). Interacts with CNPY3.
Subcellular Location: Cell membrane; Single-pass type I membrane protein, Cytoplasmic vesicle ; phagosome membrane; Single-pass type I membrane protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TLR1 are readily searchable from our website. Different antibodies against the same target such as TLR1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Bone Marrow, Embryonic Tissue, Intestine, Kidney, Liver, Lymph Node, Other, Skin, Spleen, Thymus tissues are correlated with this protein. The following patways have been known to be associated with this gene. TLR1 also interacts with the following gene(s): Irak1, Irak2, Irak4, Myd88, Nod2, Tirap, Tlr2, Traf6. Colitis, Heart Diseases, Inflammation, Kidney Diseases, Leprosy, Liver Diseases, Lung Diseases, Necrosis, Neoplasms, Experimental, Pneumonia are some of the diseases may be linked to TLR1 Antibody.
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