anti-TLR3 antibody product blog
Tags: Antibody; Polyclonal Antibody; TLR3; anti-TLR3 antibody;
The TLR3 tlr3 (Catalog #MBS2524661) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TLR3 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s TLR3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).WB: 1:500-1:2000
IHC: 1:50-1:200. Researchers should empirically determine the suitability of the TLR3 tlr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TLR3 tlr3 product has the following accession number(s) (GI #86161330) (NCBI Accession #BC096333) (Uniprot Accession #O15455). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TLR3 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Hela, Raji and K562 cell using TLR3 Polyclonal Antibody at dilution of 1:500)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver cancer using TLR3 Polyclonal Antibody at dilution of 1:50)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human lung cancer using TLR3 Polyclonal Antibody at dilution of 1:50)
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene.
Immunogen: Recombinant protein of human TLR3
Calculated MW: 104kDa. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TLR3 are readily searchable from our website. Different antibodies against the same target such as TLR3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.