anti-TLR4 antibody product blog
Tags: Antibody; TLR4; Polyclonal Antibody; anti-TLR4 antibody;
The TLR4 tlr4 (Catalog #MBS2521116) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TLR4 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s TLR4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC).IHC: 1:50-1:200. Researchers should empirically determine the suitability of the TLR4 tlr4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TLR4 tlr4 product has the following accession number(s) (GI #260401829) (NCBI Accession #ACX37356.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TLR4 Polyclonal Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TLR4 Polyclonal Antibody at dilution 1:50)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TLR4 Polyclonal Antibody at dilution 1:50)
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness.
Immunogen: Recombinant protein of human TLR4. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TLR4 are readily searchable from our website. Different antibodies against the same target such as TLR4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.