anti-TLR9 antibody product blog
Tags: Antibody; Polyclonal Antibody; TLR9; anti-TLR9 antibody;
The TLR9 tlr9 (Catalog #MBS6006102) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TLR9, CT (Toll Like Receptor 9, CD289) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s TLR9 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).Dilution: Western Blot: 1-2ug/ml
Immunohistochemistry: 2ug/ml. Researchers should empirically determine the suitability of the TLR9 tlr9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TLR9 tlr9 product has the following accession number(s) (GI #74054321) (NCBI Accession #AAZ95520.1) (Uniprot Accession #Q9NR96). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TLR9, CT (Toll Like Receptor 9, CD289) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of TLR9 in mouse spleen cell lysate with TLR9 antibody MBS6006102at (A) 0.5ug/ml, (B) 1ug/ml and (C) 2ug/ml.)
Immunohistochemistry (IHC) (Immunohistochemistry of TLR9 in mouse spleen cells with TLR9 antibody MBS6006102at 2ug/ml.)
Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between
the innate and adaptive immune responses (1,2). TLR9 forms a subfamily along with TLR7 and TLR8 that recognize viral RNA and CpG DNA sequences (3) and are localized in intracellular acidic compartments such as the phagolysosome (4). Unlike other TLRs which act through
adaptor molecules such as TOLLIP, TIRAP, TRIF, and MyD88 to activate various kinases and transcription factors to respond to potential infection (5), TLR9 is strictly dependent on MyD88 (3).
Applications:
Suitable for use in Western Blot and Immunohistochemistry,.
Immunogen: Synthetic peptide TLR9 16aa near the carboxy terminus of human TLR9 (GenBank accession no. AAH32713). Positive Control: Mouse spleen cell lysate. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TLR9 are readily searchable from our website. Different antibodies against the same target such as TLR9 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.