anti-TMC6 antibody product blog
Tags: Antibody; Polyclonal Antibody; EVER1; anti-TMC6 antibody; TMC6;
The TMC6 tmc6 (Catalog #MBS151500) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EVER1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s EVER1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).EVER1 antibody can be used for the detection of EVER1 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the TMC6 tmc6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TMC6 tmc6 product has the following accession number(s) (GI #25527208) (NCBI Accession #AAM44452) (Uniprot Accession #Q7Z403). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the EVER1 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of EVER1 in human spleen tissue lysate with EVER1 antibody at (A) 1 and (B) 2 μg/mL.)
Immunohistochemistry (IHC) (Immunohistochemistry of EVER1 in human spleen with EVER1 antibody at 2.5 μg/mL.)
Immunofluorescence (IF) (Immunofluorescence of EVER1 in Human Spleen cells with EVER1 antibody at 20 μg/mL.)
EVER1 Antibody: Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes, EVER1 and EVER2, located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. Both EVER1 and EVER2 are members of the transmembrane channel-like (TMC) protein family. EVER1 possesses eight trans-membrane domains and two leucine zipper motifs. EVER1 and EVER2 form a complex and interact with the zinc transporter 1 (ZnT-1), suggesting that EVER1 and EVER2 act to regulate cellular zinc balance.
Conjugate: Unconjugated
Immunogen: EVER1 antibody was raised against a 15 amino acid synthetic peptide from near the center of human EVER1.
Buffer: EVER1 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TMC6 are readily searchable from our website. Different antibodies against the same target such as TMC6 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.