anti-TMEM59L antibody product blog
Tags: Antibody; Polyclonal Antibody; TMEM59L; anti-TMEM59L antibody;
The TMEM59L tmem59l (Catalog #MBS9409988) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TMEM59L Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s TMEM59L can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the TMEM59L tmem59l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The TMEM59L tmem59l product has the following accession number(s) (GI #6912274) (NCBI Accession #NP_036241). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TMEM59L Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of TMEM59L in rat heart tissue lysate with TMEM59L antibody at 1 ug/mL.)
Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59L is a type I membrane glycoprotein that is expressed in the brain. A related protein, TMEM59, is a Golgi-localized protein that modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP and inhibits APP transport and shedding.
Immunogen Type: Peptide
Immunogen Description: Raised against a 19 amino acid peptide near carboxy terminus of human TMEM59L. Target Name: TMEM59L. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TMEM59L are readily searchable from our website. Different antibodies against the same target such as TMEM59L may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain tissues are correlated with this protein. Necrosis are some of the diseases may be linked to TMEM59L Antibody.