anti-TMEM67 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-TMEM67 antibody; TMEM67; meckelin isoform 1;
The TMEM67 tmem67 (Catalog #MBS837267) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Meckelin isoform 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).WB: 1:500-1:3000. Researchers should empirically determine the suitability of the TMEM67 tmem67 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TMEM67 tmem67 product has the following accession number(s) (GI #187281580) (NCBI Accession #NP_714915.3) (Uniprot Accession #Q5HYA8). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Meckelin isoform 1 antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of 30 ug of whole cell lysate (A: H1299) using a 7.5 % SDS PAGE gel and Meckelin isoform 1 antibody at a dilution of 1:1000)
Affinity purified Rabbit polyclonal Meckelin isoform 1 antibody.
Biological Significance: The protein encoded by this gene localizes to the primary cilium and to the plasma membrane. The gene functions in centriole migration to the apical membrane and formation of the primary cilium. Defects in this gene are a cause of Meckel syndrome type 3 and Joubert syndrome type 6. Cross-Reactivity: Human. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TMEM67 are readily searchable from our website. Different antibodies against the same target such as TMEM67 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Bone, Brain, Connective Tissue, Embryonic Tissue, Kidney, Liver, Lung, Muscle, Vascular tissues are correlated with this protein. Atrophy, Bardet-Biedl Syndrome, COACH syndrome, Cognition Disorders, Fibrosis, Kidney Diseases, Kidney Diseases, Cystic, Liver Cirrhosis, Meckel syndrome type 3, NEPHRONOPHTHISIS 11 are some of the diseases may be linked to Meckelin isoform 1 antibody. TMEM67 also interacts with the following gene(s): AHI1, B9D1, B9D2, CC2D2A, CEP290, MKS1, RPGRIP1L, SYNE2, TMEM216.