anti-TNF alpha antibody product blog
Tags: Antibody; Polyclonal Antibody; TNF alpha; anti-TNF ALPHA antibody;
The TNF alpha tnf (Catalog #MBS534997) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TNF alpha antibody reacts with Rat TNF alpha and may cross-react with other species as described in the data sheet. MyBioSource\'s TNF alpha can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Inhibition, Western Blot (WB).ELISA: 0.5-2 ug/ml
Inhibition: 0.07-0.1 ug/ml
WB: 0.1-0.2 ug/ml. Researchers should empirically determine the suitability of the TNF alpha tnf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TNF alpha tnf product has the following accession number(s) (GI #37210) (NCBI Accession #CAA26669.1) (Uniprot Accession #P01375). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Affinity purified Rabbit polyclonal TNF alpha antibody.
Biological Significance: TNF-alpha is a pleiotropic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-alpha is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-alpha also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. Immunogen: TNF alpha antibody was raised in rabbit using highly pure recombinant rat TNF-alpha as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TNF alpha are readily searchable from our website. Different antibodies against the same target such as TNF alpha may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Brain, Connective Tissue, Heart, Intestine, Lung, Lymph Node, Ovary, Placenta, Prostate tissues are correlated with this protein. Atherosclerosis, Colitis, Fibrosis, Inflammation, Insulin Resistance, Liver Diseases, Lung Diseases, Necrosis, Pain, Vascular Diseases are some of the diseases may be linked to TNF alpha antibody. The following patways have been known to be associated with this gene.