|The TNFRSF5 cd40 (Catalog #MBS9413810) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TNFRSF5 (Phospho-Thr254) Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s TNFRSF5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
Western blotting: 1:500~1:3000. Researchers should empirically determine the suitability of the TNFRSF5 cd40 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TNFRSF5 cd40 product has the following accession number(s) (GI #4507581) (NCBI Accession #NP_001241.1) (Uniprot Accession #P25942). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TNFRSF5 (Phospho-Thr254) Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts from COLO cells, treated with Insulin (0.01U/ml, 15mins), using TNFRSF5 (Phospho-Thr254) antibody. The lane on the right is treated with the synthesized peptide.)
Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Immunogen Type: peptide
Immunogen Description: Peptide sequence around phosphorylation site of threonine 254 (Q-E-T(p)-L-H) derived from Human TNFRSF5. Modification: Phospho-Thr254
Target Name: TNFRSF5. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TNFRSF5 are readily searchable from our website. Different antibodies against the same target such as TNFRSF5 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Kidney, Liver, Lung, Lymph, Lymph Node, Skin, Tonsil tissues are correlated with this protein. TNFRSF5 also interacts with the following gene(s): BIRC2, BIRC3, CD40LG, JAK3, NFKB1, TRAF1, TRAF2, TRAF3, TRAF5, TRAF6. Arthritis, Rheumatoid, Atherosclerosis, Cardiovascular Diseases, Disease Models, Animal, Inflammation, Kidney Diseases, Liver Diseases, Lung Diseases, Myocardial Infarction, Necrosis are some of the diseases may be linked to TNFRSF5 (Phospho-Thr254) Antibody.