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anti-TOX3 antibody product blog

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Posted on 2018-05-16 14:52:48 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; TOX3; anti-TOX3 antibody;
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The TOX3 tox3 (Catalog #MBS7046650) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TOX3 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s TOX3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Researchers should empirically determine the suitability of the TOX3 tox3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The TOX3 tox3 product has the following accession number(s) (GI #226054295) (NCBI Accession #NP_001073899.2) (Uniprot Accession #O15405). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TOX3 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot
All lanes: TOX3 antibody at 9 ug/ml
Lane 1: Mouse heart tissue
Lane 2: Mouse spleen tissue
Lane 3: Mouse brain tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 63 kDa
Observed band size: 63,24 kDa
)
Western Blot (WB) TOX3.

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human brain tissue using MBS7046650 at dilution of 1:100)
Immunohistochemistry (IHC) TOX3.

Immunohistochemistry (IHC) (Immunofluorescent analysis of HepG-2 cells using MBS7046650 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunohistochemistry (IHC) TOX3.

Transcriptional coactivator of the p300/CBP-mediated trancription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region.

Species: Human
Immunogen: Recombinant human TOX high mobility group box family member 3 protein. Conjugate: Non-conjugated
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TOX3 are readily searchable from our website. Different antibodies against the same target such as TOX3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Breast Neoplasms, Breast Neoplasms, Male, Disease Models, Animal, Hypertension, Inflammation, Kidney Diseases, Lung Neoplasms, Nerve Degeneration, Nervous System Diseases, Ovarian Neoplasms are some of the diseases may be linked to TOX3 Antibody. TOX3 also interacts with the following gene(s): FGFR2, FOS, LSP1, MAP3K1, MRPS30, RAD51B.
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