anti-tPA antibody product blog
Tags: Antibody; TPA; Polyclonal Antibody; anti-TPA antibody;
The tPA plat (Catalog #MBS536194) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The tPA antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s tPA can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Formalin, IP, RIA, WB. Researchers should empirically determine the suitability of the tPA plat for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The tPA plat product has the following accession number(s) (GI #441174) (NCBI Accession #BAA00881.1) (Uniprot Accession #P00750). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Goat polyclonal tPA antibody.
Biological Significance: Tissue plasminogen activator (TPA or PLAT) is a protein involved in the breakDaown of blood clots. It is a serine protease found on endothelial cells, the cells that line the blood vessels. As an enzyme, it catalyzes the conversion of plasminogen to plasmin, the major enzyme responsible for clot breakDaown. Immunogen: tPA antibody was raised in goat using single chain human TPA isolated from malignant melanoma (Bowes) cell culture as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing tPA are readily searchable from our website. Different antibodies against the same target such as tPA may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Arterial Occlusive Diseases, Atherosclerosis, Brain Ischemia, Cerebral Infarction, Embolism and Thrombosis, Hemorrhage, Hypertension, Myocardial Infarction, Stroke, Thrombosis are some of the diseases may be linked to tPA antibody. Bone, Brain, Embryonic Tissue, Heart, Intestine, Kidney, Liver, Lung, Muscle, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene.