anti-TRAF2 antibody product blog
Tags: Antibody; Polyclonal Antibody; TRAF2; anti-TRAF2 antibody;
The TRAF2 traf2 (Catalog #MBS9405190) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRAF2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s TRAF2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the TRAF2 traf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The TRAF2 traf2 product has the following accession number(s) (GI #55959980) (NCBI Accession #CAI15106) (Uniprot Accession #Q12933). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TRAF2 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of TRAF2 in human liver tissue lysate with TRAF2 antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.)
Immunohistochemistry (IHC) (Immunohistochemistry of TRAF2 in human liver tissue with TRAF2 antibody at 2.5 ug/mL.)
Tumor necrosis factor (TNF) receptor associated factors (TRAFs) were initially discovered as adaptor proteins that link the TNF receptor superfamily to signaling pathways and are thus important regulators of cell death and cellular response to stress. TRAF proteins share a homology region that allows them to bind to cell receptors and other TRAF proteins, causing the activation of different signal cascades depending on the TRAFs involved. For example, TRAF2 and TRAF3 directly bind to the CD40, a NF receptor superfamily member involved in inducing B cell immunity, and are critical for NF-kB activation in mouse B lymphocytes. TRAF2 along with TRAF6 has also been shown to be required for CD40 signaling in nonhemopoietic cells. TRAF2 also interacts with the TRFR superfamily member lymphotoxin-beta receptor (LTbetaR) in association with TRAF3 and the apoptosis inhibitors cIAP1 and Smac.
Immunogen Type: Peptide
Immunogen Description: Raised against a 16 amino acid peptide from near the amino terminus of human TRAF2. Target Name: TRAF2. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TRAF2 are readily searchable from our website. Different antibodies against the same target such as TRAF2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.