|The TRAFD1 trafd1 (Catalog #MBS2524231) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRAFD1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s TRAFD1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC).
IHC: 1:25-1:100. Researchers should empirically determine the suitability of the TRAFD1 trafd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TRAFD1 trafd1 product has the following accession number(s) (GI #74754309) (NCBI Accession #O14545.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TRAFD1 Polyclonal Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TRAFD1 Polyclonal Antibody at dilution 1:20)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TRAFD1 Polyclonal Antibody at dilution 1:20)
The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses. Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation.
Immunogen: Recombinant protein of human TRAFD1. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TRAFD1 are readily searchable from our website. Different antibodies against the same target such as TRAFD1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. TRAFD1 also interacts with the following gene(s): DDX58, TRAF6. Blood, Brain, Nerve tissues are correlated with this protein. Necrosis are some of the diseases may be linked to TRAFD1 Polyclonal Antibody.