|The TRIB2 trib2 (Catalog #MBS628598) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRIB2, NT (Tribbles Homolog 2, TRB-2, TRB2) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s TRIB2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500. Researchers should empirically determine the suitability of the TRIB2 trib2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TRIB2 trib2 product has the following accession number(s) (GI #11056054) (NCBI Accession #NP_067675.1) (Uniprot Accession #Q92519). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
TRIB2 is one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia.
Immunogen: Synthetic peptide selected from the N-terminal region of human TRIB2 (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TRIB2 are readily searchable from our website. Different antibodies against the same target such as TRIB2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Embryonic Tissue, Eye, Lung tissues are correlated with this protein. Cardiovascular Diseases, Cell Transformation, Neoplastic, Leukemia, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Leukemia, Myeloid, Acute, Leukemia, T-Cell, Neoplasms, Nervous System Diseases, Uveitis are some of the diseases may be linked to TRIB2, NT (Tribbles Homolog 2, TRB-2, TRB2).