anti-TRIM22 antibody product blog
Tags: Antibody; Polyclonal Antibody; TRIM22; anti-TRIM22 antibody;
The TRIM22 trim22 (Catalog #MBS9410734) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRIM22 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s TRIM22 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the TRIM22 trim22 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TRIM22 trim22 product has the following accession number(s) (GI #313760629) (NCBI Accession #NP_001186502.1) (Uniprot Accession #Q8IYM9). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TRIM22 Antibody with the following immunoassay(s):
Testing Data (Gel: 8%SDS-PAGE Lysate: 40ug A172 cellPrimary antibody: 1/250 dilution Secondary antibody dilution: 1/8000Exposure time: 3 minutes)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using at dilution 1/25.)
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon\'s antiviral effects.
Immunogen Type: Peptide
Immunogen Description: Synthetic peptide corresponding to residues near the N terminal of human tripartite motif containing 22. Target Name: TRIM22. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TRIM22 are readily searchable from our website. Different antibodies against the same target such as TRIM22 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. TRIM22 also interacts with the following gene(s): BST2, EIF4E, ISG15, MX1, PML, TAB2. Breast Neoplasms, Cell Transformation, Neoplastic, Chromosome Aberrations, Inflammation, Influenza, Human, Kidney Diseases, Kidney Neoplasms, Liver Diseases, Necrosis, Neoplasm Metastasis are some of the diseases may be linked to TRIM22 Antibody. The following patways have been known to be associated with this gene. Blood, Bone, Bone Marrow, Embryonic Tissue, Heart, Kidney, Liver, Placenta, Umbilical Cord, Uterus tissues are correlated with this protein.