anti-Trk B antibody product blog
Tags: Antibody; Polyclonal Antibody; Trk B; anti-Trk B antibody;
The Trk B ntrk2 (Catalog #MBS9406328) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Trk B (Phospho-Tyr706/Tyr707) Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Trk B can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC).Immunohistochemistry: 1:50~1:100. Researchers should empirically determine the suitability of the Trk B ntrk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Trk B ntrk2 product has the following accession number(s) (GI #55956790) (NCBI Accession #NP_001007098.1) (Uniprot Accession #Q16620). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Trk B (Phospho-Tyr706/Tyr707) Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human brain tissue using Trk B (Phospho-Tyr706/Tyr707) antibody (left)or the same antibody preincubated with blocking peptide (right).)
Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.
Immunogen Type: Peptide-KLH
Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 706/tyrosine 707 (T-D-Y(p)-Y(p)-R-V)derived from Human Trk B. Modification: Phospho-Tyr706/Tyr707
Target Name: Trk B. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Trk B are readily searchable from our website. Different antibodies against the same target such as Trk B may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Trk B also interacts with the following gene(s): BDNF, NGFR, NTF3, NTF4, SH2B1. The following patways have been known to be associated with this gene. Anxiety Disorders, Bipolar Disorder, Depressive Disorder, Disease Models, Animal, Glioma, Hyperphagia, Lung Neoplasms, Nervous System Diseases, Neuroblastoma, Obesity are some of the diseases may be linked to Trk B (Phospho-Tyr706/Tyr707) Antibody. Bone, Brain, Embryonic Tissue, Eye, Heart, Kidney, Lung, Nerve, Ovary, Thyroid tissues are correlated with this protein.