|The TRPM6 trpm6 (Catalog #MBS628253) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRPM6, ID (Transient Receptor Potential Cation Channel Subfamily M Member 6, Channel-kinase 2, Melastatin-related TRP Cation Channel 6, CHAK2) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s TRPM6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Immunohistochemistry (IHC).
Suitable for use in ELISA and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Immunohistochemistry: 1:50-1:100. Researchers should empirically determine the suitability of the TRPM6 trpm6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TRPM6 trpm6 product has the following accession number(s) (GI #293597572) (NCBI Accession #NP_001170781.1) (Uniprot Accession #Q5VYG5). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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CHAK2 is a member of the ion channel proteins. It regulates the calcium concentration in cells, which is imperative for such functions as muscle contractions and neuronal firing. It is also upregulated in certain forms of cancer and could play a role in diabetes.
Immunogen: Synthetic peptide selected from the center region of human TRPM6 (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TRPM6 are readily searchable from our website. Different antibodies against the same target such as TRPM6 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Bone, Brain, Intestine, Kidney, Liver, Lung tissues are correlated with this protein. TRPM6 also interacts with the following gene(s): TRPM7. Brain Diseases, Growth Disorders, HYPOMAGNESEMIA 1, INTESTINAL, Hypercalciuria, Hypertension, Inflammation, Kidney Diseases, Magnesium Deficiency, Neoplasms, Nephrocalcinosis are some of the diseases may be linked to TRPM6, ID (Transient Receptor Potential Cation Channel Subfamily M Member 6, Channel-kinase 2, Melastatin-related TRP Cation Channel 6, CHAK2).