anti-TRPM8 antibody product blog
Tags: Antibody; Polyclonal Antibody; TRPM8; anti-TRPM8 antibody;
The TRPM8 trpm8 (Catalog #MBS630472) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRPM8, CT (C940) (Transient Receptor Potential Cation Channel Subfamily M Member 8, Long Transient Receptor Potential Channel 6, LTrpC-6, LTrpC6, Transient Receptor Potential-p8, Trp-p8, LTRPC6, TRPP8) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s TRPM8 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC).Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:10-1:50. Researchers should empirically determine the suitability of the TRPM8 trpm8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TRPM8 trpm8 product has the following accession number(s) (GI #109689695) (NCBI Accession #NP_076985.4) (Uniprot Accession #Q3YFM7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TRPM8, CT (C940) (Transient Receptor Potential Cation Channel Subfamily M Member 8, Long Transient Receptor Potential Channel 6, LTrpC-6, LTrpC6, Transient Receptor Potential-p8, Trp-p8, LTRPC6, TRPP8) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of TRPM8 (arrow) using rabbit polyclonal TRPM8 Antibody (C-term C940).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the TRPM8 gene (Lane 2) (Origene Technologies).)
Immunohistochemistry (IHC) (Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with TRPM8 antibody (C-term C940), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
TRPM8 is a receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. It is activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH and involved in menthol sensation. It is permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium.
Immunogen: Synthetic peptide at the C-term(C940) of human TRPM8 (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TRPM8 are readily searchable from our website. Different antibodies against the same target such as TRPM8 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.