|The TRPV3 trpv3 (Catalog #MBS619510) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Vanilloid Receptor Like Protein 3 (Vanilloid Receptor-like 3, VRL 3, VRL-3, VRL3, HGNC:18084, Transient Receptor Potential Cation Channel Subfamily V Member 3, Trpv3 Heat Sensitive Channel, TRPV3) reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Vanilloid Receptor Like Protein 3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use ELISA and Western Blot.
Dilution: ELISA: 1:5000
Western Blot: 1:2000, detects the 91kD Vanilloid Receptor like Protein 3 in mouse brain tissue extract. Researchers should empirically determine the suitability of the TRPV3 trpv3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TRPV3 trpv3 product has the following accession number(s) (GI #22651775) (Uniprot Accession #Q2M3L1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Vanilloid Receptor-like 3 (VRL-3), also known as transient receptor potential cation channel subfamily V3 (TRPV3) is a 70 kD member of the vanilloid receptor/TRP gene family. It is expressed on keratinocytes and neurons, and is physiologically responsive to changes in temperature between 22 degree C and 40 degree C. Human TRPV3 is 790 amino acids (aa) in length. It is a 6 transmembrane domain protein that contains an N- and C-terminal cytoplasmic region. Three ankyrin repeats occur in the extended N-terminal cytoplasmic region (aa # 214-369). There is one alternate splice form that shows a 6 aa substituton for the C-terminal 31 amino acids. Over amino acids 6-15, human TRPV3 shares 90% aa sequence identity with mouse and canine TRPV3. TRPV3 is expressed in skin, tongue, dorsal root ganglion, trigeminal ganglion, spinal cord and brain and is thermosensitive in the physiological range of temperatures between TRPM8 and TRPV1.
Immunogen: Synthetic peptide (YRPREEEAI) corresponding to aa461-469 of mouse Vanilloid Receptor Like Protein3, (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TRPV3 are readily searchable from our website. Different antibodies against the same target such as TRPV3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.