anti-TRPV4 antibody product blog
Tags: Antibody; Polyclonal Antibody; TRPV4; anti-TRPV4 antibody;
The TRPV4 trpv4 (Catalog #MBS249674) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-TRPV4 Antibody (Internal) IHC-plus reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s TRPV4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), ELISA (EIA).IF (20 ug/ml)
IHC-P (10 ug/ml)
WB (1 - 2 ug/ml). Researchers should empirically determine the suitability of the TRPV4 trpv4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TRPV4 trpv4 product has the following accession number(s) (GI #22547184) (NCBI Accession #NP_067638.3) (Uniprot Accession #Q9HBA0). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-TRPV4 Antibody (Internal) IHC-plus with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-TRPV4 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC) (Anti-TRPV4 antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Immunofluorescence (IF) (Immunofluorescence of TRPV4 in human lung tissue with TRPV4 antibody at 20 µg/mL.)
Western Blot (WB) (Western blot analysis of TRPV4 in human testis tissue lysate with TRPV4 antibody at 1 ug/ml.)
TRPV4 Antibody, CMT2C Antibody, HMSN2C Antibody, OTRPC4 Antibody, SSQTL1 Antibody, VR-OAC Antibody, VRL-2 Antibody, Osm-9-like TRP channel 4 Antibody, SPSMA Antibody, TRP12 Antibody, VRL2 Antibody, VROAC Antibody, SMAL Antibody Description: Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca2+ potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism.
Immunogen: TRPV4 antibody was raised against 18 amino acid peptide near the center of human TRPV4.
Immunogen Description: 18 amino acid peptide near the center of human TRPV4. Antigen Modification: Internal
Target Species: Human. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TRPV4 are readily searchable from our website. Different antibodies against the same target such as TRPV4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.