anti-Tsc2 antibody product blog
Tags: Antibody; Polyclonal Antibody; TSC2; anti-TSC2 antibody; Phospho-mouse TSC2 (S1155);
The Tsc2 tsc2 (Catalog #MBS9211448) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Phospho-mouse TSC2 (S1155) Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Phospho-mouse TSC2 (S1155) can be used in a range of immunoassay formats including, but not limited to, Dot Blot (DB), ELISA (EIA).DB~~1:500. Researchers should empirically determine the suitability of the Tsc2 tsc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Tsc2 tsc2 product has the following accession number(s) (GI #9297076) (NCBI Accession #Q61037.1) (Uniprot Accession #Q61037). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Phospho-mouse TSC2 (S1155) Antibody with the following immunoassay(s):
Dot Blot (DB) (Dot blot analysis of mouse TSC2 Antibody (Phospho S1155) Phospho-specific Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.)
In complex with TSC1, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity). Specifically stimulates the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth (By similarity).
Antigen Type: Synthetic Peptide. Antigen Source: MOUSE. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Tsc2 are readily searchable from our website. Different antibodies against the same target such as Tsc2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Tsc2 also interacts with the following gene(s): Akt1, Akt2, Akt3, Prkaa1, Prkaa2, Rheb, Rps6ka1, Tsc1, Ywhab. Blood, Brain, Embryonic Tissue, Heart, Kidney, Liver, Lung, Muscle, Other, Skin tissues are correlated with this protein.