anti-TSHR antibody product blog
Tags: Antibody; TSHR; Polyclonal Antibody; anti-TSHR antibody;
The TSHR tshr (Catalog #MBS7605278) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The anti- TSHR antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s TSHR can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).WB : 1:500-1:5000 . Researchers should empirically determine the suitability of the TSHR tshr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TSHR tshr product has the following accession number(s) (GI #4883586) (NCBI Accession #AAD31568.1) (Uniprot Accession #P16473). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the anti- TSHR antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded rat brain using MBS7605278 (TSHR antibody) at dilution of 1:100)
Western Blot (WB) (HeLa cells were subjected to SDS PAGE followed by western blot with MBS7605278 (TSHR antibody) at dilution of 1:1000)
Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5).
Immunogen: Thyroid stimulating hormone receptor. Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TSHR are readily searchable from our website. Different antibodies against the same target such as TSHR may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Brain, Connective Tissue, Embryonic Tissue, Lung, Muscle, Ovary, Placenta, Thymus, Thyroid tissues are correlated with this protein. Adenoma, Carcinoma, Congenital Hypothyroidism, Disease Models, Animal, Graves Disease, Hyperthyroidism, Kidney Diseases, Thyroid Neoplasms, Thyroiditis, Autoimmune, Thyrotoxicosis are some of the diseases may be linked to anti- TSHR antibody. TSHR also interacts with the following gene(s): ADRB2, CGA, GNAQ, GNAS, LHCGR, NKX2-1, STAT3, TSHB. The following patways have been known to be associated with this gene.