anti-TTR antibody product blog
Tags: Antibody; TTR; Polyclonal Antibody; anti-TTR antibody;
The TTR ttr (Catalog #MBS9412644) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TTR antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s TTR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Western blotting: 1:500 - 1:2000. Researchers should empirically determine the suitability of the TTR ttr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TTR ttr product has the following accession number(s) (GI #4507725) (NCBI Accession #NP_000362.1) (Uniprot Accession #P02766). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TTR antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of Blood cell lysate using TTR antibody.)
This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq, Jan 2009].
Immunogen Type: Recombinant Protein
Immunogen Description: Recombinant protein of human TTR. Target Name: TTR. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TTR are readily searchable from our website. Different antibodies against the same target such as TTR may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Amyloid Neuropathies, Familial, Amyloidosis, Amyloidosis, Familial, Amyloidosis, Hereditary, Transthyretin-Related, Brain Diseases, Cardiovascular Diseases, Inflammation, Liver Diseases, Liver Neoplasms, Nervous System Diseases are some of the diseases may be linked to TTR antibody. TTR also interacts with the following gene(s): APOA1, APOA4, APP, CST3, GSN, HNF4A, IAPP, RBP4.