|The U2AF59 prp2 (Catalog #MBS5400198) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The U2AF59 Antibody FITC-Conjugated reacts with Saccharomyces cerevisae and may cross-react with other species as described in the data sheet. MyBioSource\'s U2AF59 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), IMM, Western Blot (WB).
Dot Blot: 1:10,000
Western Blot: 1:500-1:750. Researchers should empirically determine the suitability of the U2AF59 prp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The U2AF59 prp2 product has the following accession number(s) (GI #549144) (NCBI Accession #P36629.1) (Uniprot Accession #P36629). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
FITC-Conjugated Splicing factor U2AF 59 kDa subunit Antibody
Necessary for the splicing of pre-mRNA. The SF1-U2AF59-U2AF23 complex has a role in the recognition of the branch site (5\'-UACUAAC-3\'), the pyrimidine tract and the 3\'-splice site at the 3\'-end of introns.
Immunogen: Synthetic peptide taken within amino acid region 480-520 on yeast U2AF59 protein. Molecular Function: mRNA binding, snoRNA binding, nucleotide binding
Structure: Forms a heterodimer with the U2AF small subunit. Can also form a homodimer. U2AF large subunit (U2AF59), U2AF small subunit (U2AF23) and SF1 (bpb1) interact to form a complex required for complex A formation. Interacts with wat1/pop3.
Subcellular Location: Nucleus. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing U2AF59 are readily searchable from our website. Different antibodies against the same target such as U2AF59 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.